Metabolic Engineering for Stress Tolerance: Installing Osmoprotectant Synthesis Pathways
نویسندگان
چکیده
منابع مشابه
Metabolic engineering of osmoprotectant accumulation in plants.
Drought and salinity are among the worst scourges of agriculture. One effective mechanism to reduce damage from these stresses is the accumulation of high intracellular levels of osmoprotectant compounds. These compounds include proline, ectoine, betaines, polyols, and trehalose and have evolved in many different organisms. Since some crop plants have low levels of these osmoprotectants or none...
متن کاملEngineering trehalose synthesis in Lactococcus lactis for improved stress tolerance.
Trehalose accumulation is a common cell defense strategy against a variety of stressful conditions. In particular, our team detected high levels of trehalose in Propionibacterium freudenreichii in response to acid stress, a result that led to the idea that endowing Lactococcus lactis with the capacity to synthesize trehalose could improve the acid tolerance of this organism. To this end, we too...
متن کاملMetabolic engineering of Saccharomyces cerevisiae for astaxanthin production and oxidative stress tolerance.
The red carotenoid astaxanthin possesses higher antioxidant activity than other carotenoids and has great commercial potential for use in the aquaculture, pharmaceutical, and food industries. In this study, we produced astaxanthin in the budding yeast Saccharomyces cerevisiae by introducing the genes involved in astaxanthin biosynthesis of carotenogenic microorganisms. In particular, expression...
متن کاملEngineering trehalose synthesis in Lactococcus lactis for 1 improved stress tolerance
1 Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da 11 República – EAN, 2780-157 Oeiras, Portugal. 12 13 14 Running title: Engineering trehalose synthesis in Lactococcus lactis 15 16 17 *Corresponding author: Helena Santos 18 E-Mail: [email protected]; Tel. +351-214469541; Fax. +351-214469543. 19 20 21 22 23 Copyright © 2011, American Society for Microbiology and...
متن کاملGenetic engineering of glycinebetaine synthesis in plants: current status and implications for enhancement of stress tolerance.
Metabolic acclimation via the accumulation of compatible solutes is regarded as a basic strategy for the protection and survival of plants in extreme environments. Certain plants accumulate significant amounts of glycinebetaine (betaine), a compatible quaternary amine, in response to high salinity, cold and drought. It is likely that betaine is involved in the protection of macrocomponents of p...
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ژورنال
عنوان ژورنال: Annals of Botany
سال: 2000
ISSN: 0305-7364
DOI: 10.1006/anbo.2000.1254